Edmond J. Safra Biomedical Informatics Entrepreneurs Salon Presents:

Dr. Tzvika Hartman, SVP Computation, Biolojic Design

Computational design of smart antibodies

16:00 April 12 2022
Free registration required (Press here to register)

From our last meeting


A bi-monthly forum to promote entrepreneurship at the convergence of biology, medicine, and computing.
In addition to hearing industry leaders speak, participants will have the chance to look for collaborators, employees, advisors, customers, or investors.




Goal

Our goal is to generate a meeting, interaction and networking forum for academics, industry, entrepreneurs and venture capitalists interested in joining together biology, medicine and computing.

Next meeting

Our tenth meeting will take place on Tuesday, April 12 2022, in the Jaglom Auditorium, Senate building, Tel Aviv University.
The talk is titled "Computational design of smart antibodies"
featuring Dr. Tzvika Hartman, SVP Computation, Biolojic Design.

Proteins are dynamic machines that can sense changes in the environment and respond to them. They can also activate other proteins or bind different targets under different conditions.
However, currently, therapeutic proteins do not utilize the full potential of proteinst. Biolojic Design's computational platform designs dynamic antibodies that are programmed to respond to changes in the environment and to act differently under different biological conditions.
This leads to better and safer therapies. The first such computationally designed antibody has been cleared for a phase 1/2 and will enter the clinic soon. In this talk I'll start with a brief biological background and introduce some novel smart antibodies. I will continue with a description of Biolojic’s design process, which involves both computational and wet lab work.
The major part of the talk will be dedicated to the computational aspects, which aim to compute and predict antibody properties based on both public and proprietary data.

Agenda

16:00-16:15 GATHERING
16:15-16:45 TALK
16:45-17:15 Q&A
17:15-18:00 RECEPTION

Parking through gate 14, Tel Aviv University, code no. 1202741

Past meetings



May 26 2021. Yotam Drechsler, CEO and Co-founder, BrainQ technologies. "Developing a precision medicine therapy to treat stroke: At the forefront of neuroscience, machine learning, and cloud technology".

April 21 2021. Dr. Pini Akiva, CEO, KI – The Israeli Institute for Applied Research in Computational Health. "Driving computational health research towards impact".

May 7, 2020. Guy Kol (MSc, MBA) co-Founder and VP R&D, NRGene. "NRGene: Better analysis of the global natural genomic diversity to supply the world with more food".

February 23, 2020. Panelists: Yaron Breski, RM Global, Netalie Nadivi, Triventures, IritYaniv, Accelmed, Daniella Segal, Lamed Holdings. "Investments in Life Sciences in the next decade: prospects and perils".

November 14, 2019. Daniel Souroujon M.D , VP medical sciences at K Health and Tom Haramaty Algorithms team lead at K Health. "AI-driven healthcare system".

June 4, 2019. Prof. Gabi Barbash, Director, Bench to Bedside program, Weizmann Institute of Science, Founder and CEO, Consilium ltd, Former CEO of Tel Aviv Sourasky Medidical Center (1993-2015). "Forward and backward in time: From big data to precision medicine"

March 24, 2019. Dr. Shai Shen-Orr, Co-Founder and Chief Scientist, CytoReason, Faculty of Medicine, Technion, and Dr. Yair Benita, Head Science Operations, CytoReason. "Biomedical informatics: replacing the mouse model in drug development".

December 12th, 2018. Dr. Mor Amitai, CTO icarbonx Israel. "Personalized healthcare: challenges in joining biology, medicine, and computing".


Impressions from the first meeting

Organizing committee